Description
IGF-1 LR3 is a research peptide based on human insulin-like growth factor-1 that laboratories use to study growth-factor signalling, protein synthesis, and metabolic pathways in controlled in-vitro systems.
IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1)
This Long R3 variant includes a 13-amino-acid extension and an arginine substitution at position 3. These sequence changes reduce binding to IGF-binding proteins (IGFBPs) and support sustained availability in experimental models.
For laboratory research only. Not for human use.
IGF-1 Key features
- Engineered to minimise IGFBP binding and support consistent readouts in vitro.
- Supplied as a lyophilised solid for stability and straightforward storage.
- Unit size: 1 mg per vial.
- Each batch released only after stringent quality checks
Specifications

- Product name: IGF-1 LR3
- Synonyms: Long R3 IGF-1; Long Arg3 IGF-1
- Molecular formula: C400H625N111O115S9
- Molecular weight: 9,117.6 g/mol
- CAS: 946870-92-4
- Form: Lyophilised powder
- Appearance: White to off-white solid
Handling & storage
- Storage (dry): Keep vials protected from light and moisture.
- Reconstitution: Bring vial and diluent to room temperature. Reconstitute with
Bacteriostatic Water 10 ml. Swirl gently — do not vortex. - After reconstitution: Store at 2–8 °C, protect from light, use aliquots to reduce handling, and avoid repeated temperature cycling.
- Compatibility: Use only within research protocols that follow your lab’s SOPs and local regulations.
Looking for complementary materials? See
Bacteriostatic Water 10 ml and GH-axis companions such as
CJC-1295 (No DAC) 5 mg and
Ipamorelin 2 mg.
About IGF-1 LR3 in research
IGF-1 LR3 retains receptor-binding characteristics of native IGF-1 while its sequence modifications help sustain activity in vitro by limiting IGFBP interactions. Consequently, researchers use it to probe cell growth and differentiation, protein synthesis, and glucose-metabolism pathways in non-clinical models.
Synthesis & quality
Manufactured via controlled, validated peptide-synthesis processes to deliver high purity and lot-to-lot consistency. Each batch undergoes identity, purity, and appearance checks before release.
Legal & safety
XL Peptides supplies materials strictly for laboratory research. Products are not medications, foods, supplements, or cosmetics; not for human or veterinary use. By purchasing, you confirm you are a qualified researcher and will handle the material in line with your institution’s policies and applicable laws.




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